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NAT10 acetylates BCL-XL mRNA to promote the proliferation of multiple myeloma cells through PI3K-AKT pathway
Multiple myeloma (MM) is a clinically distinctive plasma cell malignancy in the bone marrow (BM), in which epigenetic abnormalities are featured prominently. Epigenetic modifications including acetylation have been deemed to contribute to tumorigenesis. N-acetyltransferase 10 (NAT10) is an important...
Autores principales: | Zhang, Yuanjiao, Deng, Zhendong, Sun, Shanliang, Xie, Siyuan, Jiang, Mingmei, Chen, Bing, Gu, Chunyan, Yang, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376478/ https://www.ncbi.nlm.nih.gov/pubmed/35978804 http://dx.doi.org/10.3389/fonc.2022.967811 |
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