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Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11

OBJECTIVE: Cholangiocarcinoma (CHOL) is a deadly cancer worldwide with limited available therapies. The aim of this study was to investigate key exosomal miRNAs and their functions in CHOL development. METHODS: Serum exosomes were isolated from patients with CHOL and healthy controls, followed by mi...

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Detalles Bibliográficos
Autores principales: Gao, Huijie, He, Zhaobin, Gao, Chao, Liu, Naiqing, Zhang, Zhaoyang, Niu, Weibo, Niu, Jun, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376483/
https://www.ncbi.nlm.nih.gov/pubmed/35978818
http://dx.doi.org/10.3389/fonc.2022.936507