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CRISPRi-mediated suppression of E. coli Nissle 1917 virulence factors: A strategy for creating an engineered probiotic using csgD gene suppression

BACKGROUND: Biofilm formation is a complex phenomenon, and it is the causative agent of several human infections. Bacterial amyloids are involved in biofilm formation leading to infection persistence. Due to antibiotic resistance, their treatment is a great challenge for physicians. Probiotics, espe...

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Detalles Bibliográficos
Autores principales:	Azam, Mohd W., Khan, Asad U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376613/ https://www.ncbi.nlm.nih.gov/pubmed/35978963 http://dx.doi.org/10.3389/fnut.2022.938989

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