Cargando…
Psychiatric risk gene transcription factor 4 preferentially regulates cortical interneuron neurogenesis during early brain development
Genetic variants within or near the transcription factor 4 gene (TCF4) are robustly implicated in psychiatric disorders including schizophrenia. However, the biological pleiotropy poses considerable obstacles to dissect the potential relationship between TCF4 and those highly heterogeneous diseases....
Autores principales: | Wang, Yuanyuan, Liu, Liya, Lin, Mingyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376727/ https://www.ncbi.nlm.nih.gov/pubmed/35965434 http://dx.doi.org/10.7555/JBR.36.20220074 |
Ejemplares similares
-
Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons
por: Rubin, Anna N., et al.
Publicado: (2020) -
Gabaergic Interneurons in Early Brain Development: Conducting and Orchestrated by Cortical Network Activity
por: Warm, Davide, et al.
Publicado: (2022) -
The Crucial Role of Atg5 in Cortical Neurogenesis During Early Brain Development
por: Lv, Xiaohui, et al.
Publicado: (2014) -
Homeostatic Regulation of Interneuron Apoptosis During Cortical Development
por: Denaxa, Myrto, et al.
Publicado: (2018) -
PDK1 regulates the survival of the developing cortical interneurons
por: Wei, Yongjie, et al.
Publicado: (2020)