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The Nucleus Bypasses Obstacles by Deforming Like a Drop with Surface Tension Mediated by Lamin A/C

Migrating cells must deform their stiff cell nucleus to move through pores and fibers in tissue. Lamin A/C is known to hinder cell migration by limiting nuclear deformation and passage through confining channels, but its role in nuclear deformation and passage through fibrous environments is less cl...

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Detalles Bibliográficos
Autores principales: Katiyar, Aditya, Zhang, Jian, Antani, Jyot D., Yu, Yifan, Scott, Kelsey L., Lele, Pushkar P., Reinhart‐King, Cynthia A., Sniadecki, Nathan J., Roux, Kyle J., Dickinson, Richard B., Lele, Tanmay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376816/
https://www.ncbi.nlm.nih.gov/pubmed/35712768
http://dx.doi.org/10.1002/advs.202201248