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Ruthenium(II)–Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis

[Image: see text] While ruthenium arene complexes have been widely investigated for their medicinal potential, studies on homologous compounds containing a tridentate tris(1-pyrazolyl)methane ligand are almost absent in the literature. Ruthenium(II) complex 1 was obtained by a modified reported proc...

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Detalles Bibliográficos
Autores principales: Cervinka, Jakub, Gobbo, Alberto, Biancalana, Lorenzo, Markova, Lenka, Novohradsky, Vojtech, Guelfi, Massimo, Zacchini, Stefano, Kasparkova, Jana, Brabec, Viktor, Marchetti, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376960/
https://www.ncbi.nlm.nih.gov/pubmed/35913426
http://dx.doi.org/10.1021/acs.jmedchem.2c00722