Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

Despite its high prevalence, the cellular and molecular mechanisms of chronic obstructive pulmonary disease (COPD) are far from being understood. Here, we determine disease-related changes in cellular and molecular compositions within the alveolar space and peripheral blood of a cohort of COPD patie...

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Detalles Bibliográficos
Autores principales: Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S., Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D., Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T., Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, Marc H., Hughes, Travis K., Ferreira, Humberto J., Hinkley, Emily, Kaltheuner, Ines H., Geyer, Matthias, Thiele, Christoph, Shalek, Alex K., Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C., Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J., Skowasch, Dirk, Schultze, Joachim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377018/
https://www.ncbi.nlm.nih.gov/pubmed/35979364
http://dx.doi.org/10.3389/fimmu.2022.917232

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