Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

BACKGROUND: Immunotherapy has proven to be an emerging treatment for non-small-cell lung cancer in recent years. Notably, smokers show higher programmed cell death ligand-1 (PD-L1) expression and better responses to PD-1/PD-L1 inhibitors than nonsmokers. Genome-wide association studies show that the...

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Detalles Bibliográficos
Autores principales: Zhu, Ping, Jin, Zhengxin, Kang, Guiyu, Jia, Yanfei, Liu, Duanrui, Zhang, Qian, Guo, Feiyang, Jia, Ying, Jiao, Yang, Li, Jingtan, Sun, Haiji, Ma, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377093/
https://www.ncbi.nlm.nih.gov/pubmed/35971127
http://dx.doi.org/10.1186/s12964-022-00934-z

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