Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome

BACKGROUND: Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic risk on these microbial profiles and their relationship to disease phenotype are...

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Detalles Bibliográficos
Autores principales: Jacobs, Jonathan P., Goudarzi, Maryam, Lagishetty, Venu, Li, Dalin, Mak, Tytus, Tong, Maomeng, Ruegger, Paul, Haritunians, Talin, Landers, Carol, Fleshner, Philip, Vasiliauskas, Eric, Ippoliti, Andrew, Melmed, Gil, Shih, David, Targan, Stephan, Borneman, James, Fornace, Albert J., McGovern, Dermot P. B., Braun, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377146/
https://www.ncbi.nlm.nih.gov/pubmed/35971134
http://dx.doi.org/10.1186/s13073-022-01099-7

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