Cargando…
Loss of MEN1 leads to renal fibrosis and decreases HGF‐Adamts5 pathway activity via an epigenetic mechanism
BACKGROUND: Renal fibrosis is a serious condition that results in the development of chronic kidney diseases. The MEN1 gene is an epigenetic regulator that encodes the menin protein and its role in kidney tissue remains unclear. METHODS: Kidney histology was examined on paraffin sections stained wit...
Autores principales: | Jin, Bangming, Zhu, Jiamei, Zhou, Yuxia, Liang, Li, Yang, Yunqiao, Xu, Lifen, Zhang, Tuo, Li, Po, Pan, Ting, Guo, Bing, Chen, Tengxiang, Li, Haiyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377152/ https://www.ncbi.nlm.nih.gov/pubmed/35968938 http://dx.doi.org/10.1002/ctm2.982 |
Ejemplares similares
-
MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation
por: Jin, Bangming, et al.
Publicado: (2023) -
Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis
por: Yang, Shu, et al.
Publicado: (2023) -
ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
por: Zitomersky, Naamah L., et al.
Publicado: (2017) -
Epigenetic Upregulation of HGF and c-Met Drives Metastasis in Hepatocellular Carcinoma
por: Ogunwobi, Olorunseun O., et al.
Publicado: (2013) -
Can ADAMTS13 Lead Us to the Paradise of Personalized Medicine?
por: Rossing, Peter, et al.
Publicado: (2013)