Identifying Drug-Induced Liver Injury Associated With Inflammation-Drug and Drug-Drug Interactions in Pharmacologic Treatments for COVID-19 by Bioinformatics and System Biology Analyses: The Role of Pregnane X Receptor

Of the patients infected with coronavirus disease 2019 (COVID-19), approximately 14–53% developed liver injury resulting in poor outcomes. Drug-induced liver injury (DILI) is the primary cause of liver injury in COVID-19 patients. In this study, we elucidated liver injury mechanism induced by drugs...

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Detalles Bibliográficos
Autores principales: Huang, Jingjing, Zhang, Zhaokang, Hao, Chenxia, Qiu, Yuzhen, Tan, Ruoming, Liu, Jialin, Wang, Xiaoli, Yang, Wanhua, Qu, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377275/
https://www.ncbi.nlm.nih.gov/pubmed/35979235
http://dx.doi.org/10.3389/fphar.2022.804189

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