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What Plasma Can Tell Us When Tissue Cannot: A Case Report of Genomic Testing in mCRPC and Clinical Response to Treatment With the PARP Inhibitor Rucaparib
BACKGROUND: The poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib was approved in the United States based on the phase 2 TRITON2 study of patients with BRCA1 or BRCA2 (BRCA)–mutated metastatic castration-resistant prostate cancer (mCRPC). Although genomic screening is recommended as part of a c...
Autores principales: | Petrylak, Daniel P., Watkins, Simon P., Loehr, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377337/ https://www.ncbi.nlm.nih.gov/pubmed/35978838 http://dx.doi.org/10.3389/fonc.2022.951348 |
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