RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress

Solving the problems that replication forks encounter when synthesizing DNA is essential to prevent genomic instability. Besides their role in DNA repair in the G2 phase, several homologous recombination proteins, specifically RAD51, have prominent roles in the S phase. Using different cellular mode...

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Detalles Bibliográficos
Autores principales: Feu, Sonia, Unzueta, Fernando, Ercilla, Amaia, Pérez-Venteo, Alejandro, Jaumot, Montserrat, Agell, Neus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377619/
https://www.ncbi.nlm.nih.gov/pubmed/35969531
http://dx.doi.org/10.1371/journal.pone.0266645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377619/
https://www.ncbi.nlm.nih.gov/pubmed/35969531
http://dx.doi.org/10.1371/journal.pone.0266645

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