Cargando…

Genistein improves mitochondrial function and inflammatory in rats with diabetic nephropathy via inhibiting MAPK/NF-κB pathway

PURPOSE: To investigate the effect of genistein on inflammation and mitochondrial function of diabetic nephropathy. METHODS: Diabetic nephropathy model was established in Sprague-Dawley rats. Automatic biochemical analyzer was employed to detect the kidney function index, serum creatinine, serum ure...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ying, Ou, Santao, Liu, Qi, Gan, Linwang, Zhang, Liling, Wang, Yujie, Qin, Jianhua, Liu, Jin, Wu, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377651/ https://www.ncbi.nlm.nih.gov/pubmed/35976278 http://dx.doi.org/10.1590/acb370601

Ejemplares similares

The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats
por: Gong, Caipan, et al.
Publicado: (2017)

Obstructive jaundice in a patient with polycystic liver disease complicated with polycystic kidney and polycystic lung: A case report
por: Zhang, Liling, et al.
Publicado: (2020)

Bone Morphogenetic Proteins 2/4 Are Upregulated during the Early Development of Vascular Calcification in Chronic Kidney Disease
por: Wei, Xiao, et al.
Publicado: (2018)

Efficacy and safety of intradialytic exercise in haemodialysis patients: a systematic review and meta-analysis
por: Pu, Jiang, et al.
Publicado: (2019)

Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury
por: Zhang, Rui, et al.
Publicado: (2017)

Genistein alleviates chronic vascular inflammatory response via the miR-21/NF-κB p65 axis in lipopolysaccharide-treated mice
por: Xie, Xiaolin, et al.
Publicado: (2021)

Altered serum metabolome associated with vascular calcification developed from CKD and the critical pathways
por: Tan, Ruyu, et al.
Publicado: (2023)

Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways
por: Chen, Xin-Sen, et al.
Publicado: (2023)

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
por: Huang, Xia, et al.
Publicado: (2017)

Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB
por: Yan, Yaoyao, et al.
Publicado: (2023)

Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling
por: Tang, Yongjun, et al.
Publicado: (2018)

Rack1 regulates pro-inflammatory cytokines by NF-κB in diabetic nephropathy
por: Wu, Keqian, et al.
Publicado: (2022)

Sanziguben polysaccharides inhibit diabetic nephropathy through NF-κB-mediated anti-inflammation
por: Zhou, Kang, et al.
Publicado: (2021)

Surfactin inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and inflammasomes in macrophages for adjuvant activity
por: Gan, Ping, et al.
Publicado: (2016)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy
por: Zhang, Mingyan, et al.
Publicado: (2018)

Genistein Promotes Anti-Heat Stress and Antioxidant Effects via the Coordinated Regulation of IIS, HSP, MAPK, DR, and Mitochondrial Pathways in Caenorhabditis elegans
por: Zhang, Sai-Ya, et al.
Publicado: (2023)

FM0807 decelerates experimental arthritis progression by inhibiting inflammatory responses and joint destruction via modulating NF-κB and MAPK pathways
por: Zhang, Nanwen, et al.
Publicado: (2019)

In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways
por: Zhang, Chao, et al.
Publicado: (2019)

Genistein Suppresses LPS-Induced Inflammatory Response through Inhibiting NF-κB following AMP Kinase Activation in RAW 264.7 Macrophages
por: Ji, Guiyuan, et al.
Publicado: (2012)

Piperine Plays an Anti-Inflammatory Role in Staphylococcus aureus Endometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice
por: Zhai, Wen-jun, et al.
Publicado: (2016)

Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways
por: Kim, Dae Won, et al.
Publicado: (2018)

Iridoid glycosides from Morinda officinalis How. exert anti-inflammatory and anti-arthritic effects through inactivating MAPK and NF-κB signaling pathways
por: Zhang, Qi, et al.
Publicado: (2020)

Morroniside Inhibits Inflammatory Bone Loss through the TRAF6-Mediated NF-κB/MAPK Signalling Pathway
por: Xiao, Jirimutu, et al.
Publicado: (2023)

Sensitization of Cervical Cancer Cells to Cisplatin by Genistein: The Role of NFκB and Akt/mTOR Signaling Pathways
por: Sahin, K., et al.
Publicado: (2012)

Protective Effect of Genistein on Condylar Cartilage through Downregulating NF-κB Expression in Experimentally Created Osteoarthritis Rats
por: Yuan, Jian, et al.
Publicado: (2019)

Effect of umbelliferone on adjuvant-induced arthritis in rats by MAPK/NF-κB pathway
por: Ouyang, Liu, et al.
Publicado: (2019)

Flemingia philippinensis Flavonoids Relieve Bone Erosion and Inflammatory Mediators in CIA Mice by Downregulating NF-κB and MAPK Pathways
por: Sun, Guangchen, et al.
Publicado: (2019)

Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-κB activation and MAPK phosphorylation
por: Kim, Seon Young, et al.
Publicado: (2017)

Inflammatory Potential of Four Different Phases of Calcium Pyrophosphate Relies on NF-κB Activation and MAPK Pathways
por: Campillo-Gimenez, Laure, et al.
Publicado: (2018)

Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling
por: Zhao, Yingzi, et al.
Publicado: (2021)

Anti-Inflammatory Effects of Weigela subsessilis Callus Extract via Suppression of MAPK and NF-κB Signaling
por: Lim, Hyeon-Ji, et al.
Publicado: (2021)

Anti‑inflammatory effects of Nypa fruticans Wurmb via NF‑κB and MAPK signaling pathways in macrophages
por: Park, Hye Jeong, et al.
Publicado: (2022)

Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways
por: Shang, Haixia, et al.
Publicado: (2019)

Polysaccharides from Liriopes Radix ameliorate streptozotocin-induced type I diabetic nephropathy via regulating NF-κB and p38 MAPK signaling pathways
por: Lu, Hung-Jen, et al.
Publicado: (2014)

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation
por: Zhuang, Yuanyuan, et al.
Publicado: (2017)

Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation
por: Liu, Yuanqi, et al.
Publicado: (2022)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Anti-Inflammatory and Gastroprotective Roles of Rabdosia inflexa through Downregulation of Pro-Inflammatory Cytokines and MAPK/NF-κB Signaling Pathways
por: Akanda, Md Rashedunnabi, et al.
Publicado: (2018)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i6a7bbiga5rk204a68tddnkjsq