Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

[Image: see text] Despite the progress made in developmental toxicology, there is a great need for in vitro tests that identify developmental toxicants in relation to human oral doses and blood concentrations. In the present study, we established the hiPSC-based UKK2 in vitro test and analyzed genom...

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Autores principales: Cherianidou, Anna, Seidel, Florian, Kappenberg, Franziska, Dreser, Nadine, Blum, Jonathan, Waldmann, Tanja, Blüthgen, Nils, Meisig, Johannes, Madjar, Katrin, Henry, Margit, Rotshteyn, Tamara, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel, Rahnenführer, Jörg, Sachinidis, Agapios, Hengstler, Jan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377669/
https://www.ncbi.nlm.nih.gov/pubmed/35416653
http://dx.doi.org/10.1021/acs.chemrestox.1c00392

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