Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2

NFAT5 is the only known mammalian tonicity-responsive transcription factor with an essential role in cellular adaptation to hypertonic stress. It is also implicated in diverse physiological and pathological processes. NFAT5 activity is tightly regulated by extracellular tonicity, but the underlying...

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Detalles Bibliográficos
Autores principales: Cheung, Chris Y., Huang, Ting-Ting, Chow, Ning, Zhang, Shuqi, Zhao, Yanxiang, Chau, Mary P., Chan, Wing Cheung, Wong, Catherine C. L., Boassa, Daniela, Phan, Sebastien, Ellisman, Mark H., Yates, John R., Xu, SongXiao, Yu, Zicheng, Zhang, Yajing, Zhang, Rui, Ng, Ling Ling, Ko, Ben C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377714/
https://www.ncbi.nlm.nih.gov/pubmed/35635291
http://dx.doi.org/10.1242/jcs.259280

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