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Functional Mapping of AKT Signaling and Biomarkers of Response from the FAIRLANE Trial of Neoadjuvant Ipatasertib plus Paclitaxel for Triple-Negative Breast Cancer

PURPOSE: Despite extensive genomic and transcriptomic profiling, it remains unknown how signaling pathways are differentially activated and how tumors are differentially sensitized to certain perturbations. Here, we aim to characterize AKT signaling activity and its association with other genomic or...

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Detalles Bibliográficos
Autores principales:	Shi, Zhen, Wulfkuhle, Julia, Nowicka, Malgorzata, Gallagher, Rosa I., Saura, Cristina, Nuciforo, Paolo G., Calvo, Isabel, Andersen, Jay, Passos-Coelho, José Luis, Gil-Gil, Miguel J., Bermejo, Begoña, Pratt, Debra A., Ciruelos, Eva M., Villagrasa, Patricia, Wongchenko, Matthew J., Petricoin, Emanuel F., Oliveira, Mafalda, Isakoff, Steven J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Precision Medicine and Imaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377742/ https://www.ncbi.nlm.nih.gov/pubmed/34907082 http://dx.doi.org/10.1158/1078-0432.CCR-21-2498

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