Nonclinical Characterization of Bexmarilimab, a Clever-1–Targeting Antibody for Supporting Immune Defense Against Cancers

Common lymphatic endothelial and vascular endothelial receptor-1 (Clever-1) is a multifunctional type-1 transmembrane protein that plays an important role in immunosuppression against tumors. Clever-1 is highly expressed in a subset of human tumor-associated macrophages and associated with poor surv...

Descripción completa

Detalles Bibliográficos
Autores principales: Hollmén, Maija, Maksimow, Mikael, Rannikko, Jenna H., Karvonen, Matti K., Vainio, Marita, Jalkanen, Sirpa, Jalkanen, Markku, Mandelin, Jami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Large Molecule Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377746/
https://www.ncbi.nlm.nih.gov/pubmed/35500016
http://dx.doi.org/10.1158/1535-7163.MCT-21-0840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377746/
https://www.ncbi.nlm.nih.gov/pubmed/35500016
http://dx.doi.org/10.1158/1535-7163.MCT-21-0840

Ejemplares similares