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Nonclinical Characterization of Bexmarilimab, a Clever-1–Targeting Antibody for Supporting Immune Defense Against Cancers

Common lymphatic endothelial and vascular endothelial receptor-1 (Clever-1) is a multifunctional type-1 transmembrane protein that plays an important role in immunosuppression against tumors. Clever-1 is highly expressed in a subset of human tumor-associated macrophages and associated with poor surv...

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Detalles Bibliográficos
Autores principales:	Hollmén, Maija, Maksimow, Mikael, Rannikko, Jenna H., Karvonen, Matti K., Vainio, Marita, Jalkanen, Sirpa, Jalkanen, Markku, Mandelin, Jami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Large Molecule Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377746/ https://www.ncbi.nlm.nih.gov/pubmed/35500016 http://dx.doi.org/10.1158/1535-7163.MCT-21-0840

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