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Circulating CD137(+) T Cells Correlate with Improved Response to Anti-PD1 Immunotherapy in Patients with Cancer
PURPOSE: CD137 molecule is expressed by activated lymphocytes, and in patients with cancer identifies the tumor-reactive T cells. In solid tumors, high levels of circulating CD137(+) T cells are associated with the clinical response and the disease-free status. Here, we examined the role of the CD13...
Autores principales: | Zizzari, Ilaria Grazia, Di Filippo, Alessandra, Botticelli, Andrea, Strigari, Lidia, Pernazza, Angelina, Rullo, Emma, Pignataro, Maria Gemma, Ugolini, Alessio, Scirocchi, Fabio, Di Pietro, Francesca Romana, Rossi, Ernesto, Gelibter, Alain, Schinzari, Giovanni, D'Amati, Giulia, Rughetti, Aurelia, Marchetti, Paolo, Nuti, Marianna, Napoletano, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377756/ https://www.ncbi.nlm.nih.gov/pubmed/34980602 http://dx.doi.org/10.1158/1078-0432.CCR-21-2918 |
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