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Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377908/ https://www.ncbi.nlm.nih.gov/pubmed/35978641 http://dx.doi.org/10.1155/2022/6293095 |
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author | Yao, Peilin Jiang, Jiaxuan Kong, Zhenyang |
author_facet | Yao, Peilin Jiang, Jiaxuan Kong, Zhenyang |
author_sort | Yao, Peilin |
collection | PubMed |
description | With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mortality rate is 62%, which is more than twice that of developed countries. This paper is aimed at observing the microscopic effects of probiotics derived from dairy products using Caco-2 cells on intestinal barrier function. Based on the above background, the purpose of this study was to construct a Caco-2 cell model under microscope to study the effect of probiotics on intestinal barrier function. This study first describes the background knowledge of the integration of modern microscope technology and medical field and the correlation between them. The results showed that the relative adhesion rates of Lactobacillus bulgaricus, Lactobacillus acidophilus, and Streptococcus thermophilus were 4.67 ± 0.07%, 11.53 ± 0.06%, and 18.31 ± 0.08%, respectively, which were lower than those in the normal group. The production of antibacterial substances can inhibit intestinal pathogens and adjust the balance of intestinal flora. |
format | Online Article Text |
id | pubmed-9377908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93779082022-08-16 Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope Yao, Peilin Jiang, Jiaxuan Kong, Zhenyang Biomed Res Int Research Article With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mortality rate is 62%, which is more than twice that of developed countries. This paper is aimed at observing the microscopic effects of probiotics derived from dairy products using Caco-2 cells on intestinal barrier function. Based on the above background, the purpose of this study was to construct a Caco-2 cell model under microscope to study the effect of probiotics on intestinal barrier function. This study first describes the background knowledge of the integration of modern microscope technology and medical field and the correlation between them. The results showed that the relative adhesion rates of Lactobacillus bulgaricus, Lactobacillus acidophilus, and Streptococcus thermophilus were 4.67 ± 0.07%, 11.53 ± 0.06%, and 18.31 ± 0.08%, respectively, which were lower than those in the normal group. The production of antibacterial substances can inhibit intestinal pathogens and adjust the balance of intestinal flora. Hindawi 2022-08-08 /pmc/articles/PMC9377908/ /pubmed/35978641 http://dx.doi.org/10.1155/2022/6293095 Text en Copyright © 2022 Peilin Yao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Yao, Peilin Jiang, Jiaxuan Kong, Zhenyang Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title | Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title_full | Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title_fullStr | Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title_full_unstemmed | Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title_short | Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope |
title_sort | probiotics from dairy products on intestinal barrier function using caco-2 cells under microscope |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377908/ https://www.ncbi.nlm.nih.gov/pubmed/35978641 http://dx.doi.org/10.1155/2022/6293095 |
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