Cargando…

Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope

With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Peilin, Jiang, Jiaxuan, Kong, Zhenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377908/
https://www.ncbi.nlm.nih.gov/pubmed/35978641
http://dx.doi.org/10.1155/2022/6293095
_version_ 1784768433305419776
author Yao, Peilin
Jiang, Jiaxuan
Kong, Zhenyang
author_facet Yao, Peilin
Jiang, Jiaxuan
Kong, Zhenyang
author_sort Yao, Peilin
collection PubMed
description With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mortality rate is 62%, which is more than twice that of developed countries. This paper is aimed at observing the microscopic effects of probiotics derived from dairy products using Caco-2 cells on intestinal barrier function. Based on the above background, the purpose of this study was to construct a Caco-2 cell model under microscope to study the effect of probiotics on intestinal barrier function. This study first describes the background knowledge of the integration of modern microscope technology and medical field and the correlation between them. The results showed that the relative adhesion rates of Lactobacillus bulgaricus, Lactobacillus acidophilus, and Streptococcus thermophilus were 4.67 ± 0.07%, 11.53 ± 0.06%, and 18.31 ± 0.08%, respectively, which were lower than those in the normal group. The production of antibacterial substances can inhibit intestinal pathogens and adjust the balance of intestinal flora.
format Online
Article
Text
id pubmed-9377908
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-93779082022-08-16 Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope Yao, Peilin Jiang, Jiaxuan Kong, Zhenyang Biomed Res Int Research Article With the continuous improvement of human living standards, people's demand for health has become an important international research hotspot. In recent years, 41.3% of the total incidence of multiple organ failure (MOF) caused by dysfunction of the intestinal screen was found every year. The mortality rate is 62%, which is more than twice that of developed countries. This paper is aimed at observing the microscopic effects of probiotics derived from dairy products using Caco-2 cells on intestinal barrier function. Based on the above background, the purpose of this study was to construct a Caco-2 cell model under microscope to study the effect of probiotics on intestinal barrier function. This study first describes the background knowledge of the integration of modern microscope technology and medical field and the correlation between them. The results showed that the relative adhesion rates of Lactobacillus bulgaricus, Lactobacillus acidophilus, and Streptococcus thermophilus were 4.67 ± 0.07%, 11.53 ± 0.06%, and 18.31 ± 0.08%, respectively, which were lower than those in the normal group. The production of antibacterial substances can inhibit intestinal pathogens and adjust the balance of intestinal flora. Hindawi 2022-08-08 /pmc/articles/PMC9377908/ /pubmed/35978641 http://dx.doi.org/10.1155/2022/6293095 Text en Copyright © 2022 Peilin Yao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yao, Peilin
Jiang, Jiaxuan
Kong, Zhenyang
Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title_full Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title_fullStr Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title_full_unstemmed Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title_short Probiotics from Dairy Products on Intestinal Barrier Function Using Caco-2 Cells under Microscope
title_sort probiotics from dairy products on intestinal barrier function using caco-2 cells under microscope
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377908/
https://www.ncbi.nlm.nih.gov/pubmed/35978641
http://dx.doi.org/10.1155/2022/6293095
work_keys_str_mv AT yaopeilin probioticsfromdairyproductsonintestinalbarrierfunctionusingcaco2cellsundermicroscope
AT jiangjiaxuan probioticsfromdairyproductsonintestinalbarrierfunctionusingcaco2cellsundermicroscope
AT kongzhenyang probioticsfromdairyproductsonintestinalbarrierfunctionusingcaco2cellsundermicroscope