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Repeated Low-Dose Streptozotocin and Alloxan Induced Long-Term and Stable Type 1 Diabetes Model in Beagle Dogs
Type 1 diabetes mellitus (T1DM) is a chronic disease represented by insulin-causing pancreatic β-cell disruption and hyperglycemia. Therefore, it is necessary to establish a variety of animal models of diabetes to study the pathogenesis and pathophysiology of it. However, there are few reports on th...
Autores principales: | Han, Qingyue, Sun, Jie, Xie, Wenting, Bai, Yuman, Wang, Shuzhou, Huang, Jianjia, Zhou, Shuilian, Li, Quanwei, Zhang, Hui, Tang, Zhaoxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377912/ https://www.ncbi.nlm.nih.gov/pubmed/35978645 http://dx.doi.org/10.1155/2022/5422287 |
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