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Chronic Cerebral Hypoperfusion Aggravates Parkinson's Disease Dementia-Like Symptoms and Pathology in 6-OHDA-Lesioned Rat through Interfering with Sphingolipid Metabolism

Chronic cerebral hypoperfusion (CCH) is a cardinal risk factor for Parkinson's disease dementia (PDD), but this potential causality lacks mechanistic evidence. We selected bilateral common carotid artery occlusion (BCCAO) to simulate chronic cerebral hypoperfusion in the rat model of PD induced...

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Detalles Bibliográficos
Autores principales:	Fan, Yaohua, Li, Mengzhu, Wu, Chunxiao, Wu, Yubiao, Han, Jiajun, Wu, Peipei, Huang, Zifeng, Wang, Qizhang, Zhao, Lijun, Chen, Dongfeng, Zhu, Meiling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377946/ https://www.ncbi.nlm.nih.gov/pubmed/35979400 http://dx.doi.org/10.1155/2022/5392966

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