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Too advanced for assessment? Advanced materials, nanomedicine and the environment

Advanced materials, and nanomaterials, are promising for healthcare applications and are in particular in the spotlight of medical innovation since rapidly developed nano-formulated vaccines provide relief in the SARS-CoV-2 pandemic. Further increased rapid growth is to be expected as more and more...

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Autores principales: Berkner, Silvia, Schwirn, Kathrin, Voelker, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378259/
https://www.ncbi.nlm.nih.gov/pubmed/35990895
http://dx.doi.org/10.1186/s12302-022-00647-7
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author Berkner, Silvia
Schwirn, Kathrin
Voelker, Doris
author_facet Berkner, Silvia
Schwirn, Kathrin
Voelker, Doris
author_sort Berkner, Silvia
collection PubMed
description Advanced materials, and nanomaterials, are promising for healthcare applications and are in particular in the spotlight of medical innovation since rapidly developed nano-formulated vaccines provide relief in the SARS-CoV-2 pandemic. Further increased rapid growth is to be expected as more and more products are in development and reach the market, beneficial for human health. However, the human body is not a dead end and these products are likely to enter the environment, whereas their fate and effects in the environment are unknown. This part of the life-cycle of advanced medicinal products tends to be overlooked, if the perspective is human-centered and excludes the connectedness of human activity with, and consequences for our environment. Gaps are reviewed that exist in awareness, perspective taking, inclusion of environmental concerns into research and product development and also in available methodologies and regulatory guidance. To bridge these gaps, possible ways forward start to emerge, that could help to find a more integrative way of assessing human and environmental safety for advanced material medicinal products and nanomedicines.
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spelling pubmed-93782592022-08-16 Too advanced for assessment? Advanced materials, nanomedicine and the environment Berkner, Silvia Schwirn, Kathrin Voelker, Doris Environ Sci Eur Review Advanced materials, and nanomaterials, are promising for healthcare applications and are in particular in the spotlight of medical innovation since rapidly developed nano-formulated vaccines provide relief in the SARS-CoV-2 pandemic. Further increased rapid growth is to be expected as more and more products are in development and reach the market, beneficial for human health. However, the human body is not a dead end and these products are likely to enter the environment, whereas their fate and effects in the environment are unknown. This part of the life-cycle of advanced medicinal products tends to be overlooked, if the perspective is human-centered and excludes the connectedness of human activity with, and consequences for our environment. Gaps are reviewed that exist in awareness, perspective taking, inclusion of environmental concerns into research and product development and also in available methodologies and regulatory guidance. To bridge these gaps, possible ways forward start to emerge, that could help to find a more integrative way of assessing human and environmental safety for advanced material medicinal products and nanomedicines. Springer Berlin Heidelberg 2022-08-16 2022 /pmc/articles/PMC9378259/ /pubmed/35990895 http://dx.doi.org/10.1186/s12302-022-00647-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Berkner, Silvia
Schwirn, Kathrin
Voelker, Doris
Too advanced for assessment? Advanced materials, nanomedicine and the environment
title Too advanced for assessment? Advanced materials, nanomedicine and the environment
title_full Too advanced for assessment? Advanced materials, nanomedicine and the environment
title_fullStr Too advanced for assessment? Advanced materials, nanomedicine and the environment
title_full_unstemmed Too advanced for assessment? Advanced materials, nanomedicine and the environment
title_short Too advanced for assessment? Advanced materials, nanomedicine and the environment
title_sort too advanced for assessment? advanced materials, nanomedicine and the environment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378259/
https://www.ncbi.nlm.nih.gov/pubmed/35990895
http://dx.doi.org/10.1186/s12302-022-00647-7
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