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Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro

Technologies that profile chromatin modifications at single-cell resolution offer enormous promise for functional genomic characterization, but the sparsity of the measurements and integrating multiple binding maps represent substantial challenges. Here we introduce scCUT&Tag-pro, a multimodal a...

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Detalles Bibliográficos
Autores principales: Zhang, Bingjie, Srivastava, Avi, Mimitou, Eleni, Stuart, Tim, Raimondi, Ivan, Hao, Yuhan, Smibert, Peter, Satija, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378363/
https://www.ncbi.nlm.nih.gov/pubmed/35332340
http://dx.doi.org/10.1038/s41587-022-01250-0