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Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer

OBJECTIVES: To analyze the application efficiency of two tracers for sentinel lymph node mapping in patients with endometrial cancer. METHODS: The records of endometrial cancer patients treated in our hospital from July 2019 to July 2021 were selected. Among them, 29 patients received methylene blue...

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Autores principales: Zhang, Weifeng, Shu, Yan, Ni, Dongmei, Wan, Zeqiu, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378394/
https://www.ncbi.nlm.nih.gov/pubmed/35991230
http://dx.doi.org/10.12669/pjms.38.6.5714
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author Zhang, Weifeng
Shu, Yan
Ni, Dongmei
Wan, Zeqiu
Yang, Shuying
author_facet Zhang, Weifeng
Shu, Yan
Ni, Dongmei
Wan, Zeqiu
Yang, Shuying
author_sort Zhang, Weifeng
collection PubMed
description OBJECTIVES: To analyze the application efficiency of two tracers for sentinel lymph node mapping in patients with endometrial cancer. METHODS: The records of endometrial cancer patients treated in our hospital from July 2019 to July 2021 were selected. Among them, 29 patients received methylene blue suspension injection and 33 patients received nano activated carbon suspension injection. The staining of sentinel lymph nodes was recorded and the application efficiency of two different tracers were analyzed. RESULTS: Total detection rate, average number of sentinel lymph nodes and bilateral detection rate of nano activated carbon suspension injection were significantly higher than those of methylene blue suspension injection (P<0.05). Detection accuracy, positive predictive value and sensitivity of nano activated carbon suspension injection were significantly higher than those of methylene blue suspension injection (P<0.05). Incidence of complications was the same in the two groups (P>0.05). Tracing time of nano activated carbon suspension injection was significantly lower than that of methylene blue suspension injection, and the total duration was significantly higher than that of methylene blue suspension injection (P<0.05). CONCLUSION: Nano activated carbon can obtain good detection effect in sentinel lymph node recognition in endometrial cancer patients, with shorter tracing time and higher total duration than methylene blue suspension.
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spelling pubmed-93783942022-08-19 Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer Zhang, Weifeng Shu, Yan Ni, Dongmei Wan, Zeqiu Yang, Shuying Pak J Med Sci Original Article OBJECTIVES: To analyze the application efficiency of two tracers for sentinel lymph node mapping in patients with endometrial cancer. METHODS: The records of endometrial cancer patients treated in our hospital from July 2019 to July 2021 were selected. Among them, 29 patients received methylene blue suspension injection and 33 patients received nano activated carbon suspension injection. The staining of sentinel lymph nodes was recorded and the application efficiency of two different tracers were analyzed. RESULTS: Total detection rate, average number of sentinel lymph nodes and bilateral detection rate of nano activated carbon suspension injection were significantly higher than those of methylene blue suspension injection (P<0.05). Detection accuracy, positive predictive value and sensitivity of nano activated carbon suspension injection were significantly higher than those of methylene blue suspension injection (P<0.05). Incidence of complications was the same in the two groups (P>0.05). Tracing time of nano activated carbon suspension injection was significantly lower than that of methylene blue suspension injection, and the total duration was significantly higher than that of methylene blue suspension injection (P<0.05). CONCLUSION: Nano activated carbon can obtain good detection effect in sentinel lymph node recognition in endometrial cancer patients, with shorter tracing time and higher total duration than methylene blue suspension. Professional Medical Publications 2022 /pmc/articles/PMC9378394/ /pubmed/35991230 http://dx.doi.org/10.12669/pjms.38.6.5714 Text en Copyright: © Pakistan Journal of Medical Sciences https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zhang, Weifeng
Shu, Yan
Ni, Dongmei
Wan, Zeqiu
Yang, Shuying
Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title_full Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title_fullStr Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title_full_unstemmed Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title_short Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
title_sort comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378394/
https://www.ncbi.nlm.nih.gov/pubmed/35991230
http://dx.doi.org/10.12669/pjms.38.6.5714
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