Cancer Immunotherapy based on Image-guided STING Activation by Nucleotide Nanocomplex-Decorated Ultrasound Microbubbles

The cytosolic innate immune sensor cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is crucial for priming adaptive antitumour immunity through antigen-presenting cells (APCs). Natural agonists such as cyclic dinucleotides (CDNs) activate the cGAS-STING pathway, but their...

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Detalles Bibliográficos
Autores principales: Li, Xuefeng, Khorsandi, Sina, Wang, Yifan, Santelli, Julien, Huntoon, Kristin, Nguyen, Nhu, Yang, Mingming, Lee, Daeyong, Lu, Yifei, Gao, Ruoqi, Kim, Betty Y.S., de Gracia Lux, Caroline, Mattrey, Robert F., Jiang, Wen, Lux, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378430/
https://www.ncbi.nlm.nih.gov/pubmed/35637356
http://dx.doi.org/10.1038/s41565-022-01134-z

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