Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically‐induced and immune‐mediated mouse models of multiple sclerosis

Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease characterized by inflammation, demyelination, and neurodegeneration. The ideal MS therapy would both specifically inhibit the underlying autoimmune response and promote repair/regeneration of myelin as well as maintenance o...

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Detalles Bibliográficos
Autores principales: Titus, Haley E., Xu, Huan, Robinson, Andrew P., Patel, Priyam A., Chen, Yanan, Fantini, Damiano, Eaton, Valerie, Karl, Molly, Garrison, Eric D., Rose, Indigo V. L., Chiang, Ming Yi, Podojil, Joseph R., Balabanov, Roumen, Liddelow, Shane A., Miller, Robert H., Popko, Brian, Miller, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378523/
https://www.ncbi.nlm.nih.gov/pubmed/35809238
http://dx.doi.org/10.1002/glia.24231

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