Cargando…
Cortical inhibition in neurofibromatosis type 1 is modulated by lovastatin, as demonstrated by a randomized, triple-blind, placebo-controlled clinical trial
Neurofibromatosis type 1 (NF1) is associated with GABAergic dysfunction which has been suggested as the underlying cause of cognitive impairments. Previous intervention trials investigated the statins’ effects using cognitive outcome measures. However, available outcome measures have led to inconclu...
Autores principales: | Bernardino, Inês, Dionísio, Ana, Castelo-Branco, Miguel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378617/ https://www.ncbi.nlm.nih.gov/pubmed/35970940 http://dx.doi.org/10.1038/s41598-022-17873-x |
Ejemplares similares
-
A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I
por: Bearden, Carrie E., et al.
Publicado: (2016) -
Motor Cortex Excitation/Inhibition Imbalance in Young Adults With Autism Spectrum Disorder: A MRS-TMS Approach
por: Bernardino, Inês, et al.
Publicado: (2022) -
Gyrification, cortical and subcortical morphometry in neurofibromatosis type 1: an uneven profile of developmental abnormalities
por: Violante, Inês R, et al.
Publicado: (2013) -
Oscillatory motor patterning is impaired in neurofibromatosis type 1: a behavioural, EEG and fMRI study
por: Silva, Gilberto, et al.
Publicado: (2018) -
Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin
por: Kolanczyk, Mateusz, et al.
Publicado: (2008)