PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis

RIG-I-like receptors (RLRs), protein kinase R (PKR), and endosomal Toll-like receptor 3 (TLR3) sense viral non-self RNA and are involved in cell fate determination. However, the mechanisms by which intracellular RNA induces apoptosis, particularly the role of each RNA sensor, remain unclear. We perf...

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Detalles Bibliográficos
Autores principales: Zuo, Wenjie, Wakimoto, Mai, Kozaiwa, Noriyasu, Shirasaka, Yutaro, Oh, Seong-Wook, Fujiwara, Shiori, Miyachi, Hitoshi, Kogure, Amane, Kato, Hiroki, Fujita, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378677/
https://www.ncbi.nlm.nih.gov/pubmed/35970851
http://dx.doi.org/10.1038/s41419-022-05101-3

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