Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands

Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all available treatments, including natural killer (NK) cell immunotherapy. However, the factors mediating NK cell evasion in GBM remain largely unclear. Here, we report that EZH2-92aa, a protein encoded by cir...

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Detalles Bibliográficos
Autores principales: Zhong, Jian, Yang, Xuesong, Chen, Junju, He, Kejun, Gao, Xinya, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Xiao, Feizhe, An, Lele, Wang, Xiuxing, Shi, Yu, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378736/
https://www.ncbi.nlm.nih.gov/pubmed/35970825
http://dx.doi.org/10.1038/s41467-022-32311-2

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