The HMGB1 (C106A) mutation inhibits IL-10-producing CD19(hi)FcγRIIb(hi) B cell expansion by suppressing STAT3 activation in mice

Regulatory B cells have important roles in inflammation and autoimmune diseases. A newly discovered subpopulation of B cells with a CD19(hi)FcγRIIb(hi) phenotype inhibits the proliferation of CD4(+) T cells by secreting interleukin (IL)-10. The expansion of CD19(hi)FcγRIIb(hi) B cells in mouse splee...

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Detalles Bibliográficos
Autores principales: Liu, Mengru, Zhou, Jingwen, Yin, Rui, Yin, Hui, Ding, Yue, Ma, Feng, Qian, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378787/
https://www.ncbi.nlm.nih.gov/pubmed/35983056
http://dx.doi.org/10.3389/fimmu.2022.975551

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