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Novel insertion/deletion polymorphisms and genetic features of the shadow of prion protein gene (SPRN) in dogs, a prion-resistant animal

Prion diseases are fatal infectious neurodegenerative disorders that are induced by misfolded prion protein (PrP(Sc)). Previous studies have reported that the shadow of prion protein (Sho) encoded by the shadow of prion protein gene (SPRN) plays a critical role in stimulating the conversion process...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Chan, Kim, Hyeon-Ho, Kim, An-Dang, Jeong, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378991/
https://www.ncbi.nlm.nih.gov/pubmed/35982928
http://dx.doi.org/10.3389/fvets.2022.942289