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Responses of regulatory and effector T-cells to low-dose interleukin-2 differ depending on the immune environment after allogeneic stem cell transplantation

CD4(+)Foxp3(+) regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation (HSCT). Tregs promptly respond to low concentrations of IL-2 through the constitutive expression of high-affinity IL-2 receptors. It has been...

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Detalles Bibliográficos
Autores principales:	Meguri, Yusuke, Asano, Takeru, Yoshioka, Takanori, Iwamoto, Miki, Ikegawa, Shuntaro, Sugiura, Hiroyuki, Kishi, Yuriko, Nakamura, Makoto, Sando, Yasuhisa, Kondo, Takumi, Sumii, Yuichi, Maeda, Yoshinobu, Matsuoka, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379320/ https://www.ncbi.nlm.nih.gov/pubmed/35983059 http://dx.doi.org/10.3389/fimmu.2022.891925

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