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Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease
BACKGROUND: Kawasaki disease (KD) is an acute vasculitis that may result in permanent coronary artery damage with unknown etiology. Endothelial cell (EC) dysfunction and platelet hyperactivity are the hallmarks of KD. Platelets are involved in the development of endothelial dysfunction. MiR-223 tran...
Autores principales: | Guo, Manli, Fan, Shunyang, Chen, Qian, Jia, Cuiping, Qiu, Miaoyun, Bu, Yun, Tang, Wai Ho, Zhang, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379370/ https://www.ncbi.nlm.nih.gov/pubmed/35983051 http://dx.doi.org/10.3389/fimmu.2022.922868 |
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