Cargando…
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
During tumor progression, tumor cells are exposed to various stress conditions, which result in endoplasmic reticulum (ER) stress and activate the unfolded protein response (UPR) to restore ER homeostasis. Accumulating evidence reported the orchestrating role of ER stress in epithelial-mesenchymal t...
Autores principales: | Yuan, Hongyu, Zhao, Zitong, Guo, Zichan, Ma, Liying, Han, Jing, Song, Yongmei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379397/ https://www.ncbi.nlm.nih.gov/pubmed/35982901 http://dx.doi.org/10.7150/ijbs.72838 |
Ejemplares similares
-
Hypoxia-induced TMTC3 expression in esophageal squamous cell carcinoma potentiates tumor angiogenesis through Rho GTPase/STAT3/VEGFA pathway
por: Yuan, Hongyu, et al.
Publicado: (2023) -
Porcine Circovirus 2 Deploys PERK Pathway and GRP78 for Its Enhanced Replication in PK-15 Cells
por: Zhou, Yingshan, et al.
Publicado: (2016) -
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT
por: Huang, Peng, et al.
Publicado: (2020) -
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction
por: Ha, Dat P., et al.
Publicado: (2021) -
Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites
por: Eisenhaber, Birgit, et al.
Publicado: (2021)