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Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells

Pancreatic cancer (PC) is a devastating solid malignancy with a dismal prognosis. The treatment of metastatic PC is a current challenge for medical oncologists due to a lack of early detection, drug resistance, and relapse. Therefore, potential biomarkers and effective therapeutic targets for PC are...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqun, Ji, Shenying, Zhang, Xiangyu, Lu, Mengyun, Hu, Yihong, Han, Yucheng, Shui, Guanghou, Lam, Sin Man, Zou, Xianqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379408/
https://www.ncbi.nlm.nih.gov/pubmed/35982909
http://dx.doi.org/10.7150/ijbs.70007