Cargando…
Minding the gap: Unlockingthe therapeutic potentialof aptamers and making up for lost time
Aptamers are RNAs that can bind proteins directly and modulate protein-protein interactions. Given their therapeutic potential, aptamers would be expected to capture the interest of both scientists and investors. However, concerns regarding safety, efficacy, and delivery have delayed aptamer develop...
Autores principales: | Di Ruscio, Annalisa, de Franciscis, Vittorio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379498/ https://www.ncbi.nlm.nih.gov/pubmed/35991313 http://dx.doi.org/10.1016/j.omtn.2022.07.012 |
Ejemplares similares
-
The roles and therapeutic potentialof mesenchymal stem/stromal cells and their extracellular vesicles in tendinopathies
por: Quintero, Daniel, et al.
Publicado: (2023) -
Aptamer-Mediated Targeted Delivery of Therapeutics: An Update
por: Catuogno, Silvia, et al.
Publicado: (2016) -
Coupling Aptamers to Short Interfering RNAs as Therapeutics
por: Cerchia, Laura, et al.
Publicado: (2011) -
Aptamer Chimeras for Therapeutic Delivery: The Challenging Perspectives
por: Esposito, Carla Lucia, et al.
Publicado: (2018) -
Aptamer-mediated selective delivery of short RNA therapeutics in cancer cells
por: Esposito, Carla Lucia, et al.
Publicado: (2014)