The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms

The transcriptional corepressor BASP1 requires N-terminal myristoylation for its activity and functions through interactions with nuclear lipids. Here we determine the role of BASP1 lipidation in histone modification and the modulation of chromatin accessibility. We find that the removal of the acti...

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Detalles Bibliográficos
Autores principales: Moorhouse, Alexander J., Loats, Amy E., Medler, Kathryn F., Roberts, Stefan G.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379585/
https://www.ncbi.nlm.nih.gov/pubmed/35982799
http://dx.doi.org/10.1016/j.isci.2022.104796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379585/
https://www.ncbi.nlm.nih.gov/pubmed/35982799
http://dx.doi.org/10.1016/j.isci.2022.104796

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