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In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia
BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to ma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SBDR - Society for Biomedical Diabetes Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380085/ https://www.ncbi.nlm.nih.gov/pubmed/34852895 http://dx.doi.org/10.1900/RDS.2021.17.50 |
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author | Russo, María Paula Fosser, Santiago Nicolas Marquez Elizondo, Cristina María Giunta, Diego Hernán Fuentes, Nora Angélica Grande-Ratti, María Florencia |
author_facet | Russo, María Paula Fosser, Santiago Nicolas Marquez Elizondo, Cristina María Giunta, Diego Hernán Fuentes, Nora Angélica Grande-Ratti, María Florencia |
author_sort | Russo, María Paula |
collection | PubMed |
description | BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality. |
format | Online Article Text |
id | pubmed-9380085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SBDR - Society for Biomedical Diabetes Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-93800852022-08-30 In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia Russo, María Paula Fosser, Santiago Nicolas Marquez Elizondo, Cristina María Giunta, Diego Hernán Fuentes, Nora Angélica Grande-Ratti, María Florencia Rev Diabet Stud Original Data BACKGROUND: Stress-induced hyperglycemia is a phenomenon that occurs typically in patients hospitalized for acute disease and resolves spontaneously after regression of the acute illness. However, it can also occur in diabetes patients, a fact that is sometimes overlooked. It is thus important to make a proper diabetes diagnosis if hospitalized patients with episodes of hyperglycemia with and without diabetes are studied. AIMS: To estimate the extent of the association between stress-induced hyperglycemia and in-hospital mortality in patients with hospital hyperglycemia (HH), and to explore potential differences between patients diagnosed with diabetes (HH-DBT) and those with stress-induced hyperglycemia (SH), but not diagnosed with diabetes. METHODS: A cohort of adults with hospital hyperglycemia admitted to a tertiary, university hospital in Buenos Aires, Argentina, was analyzed retrospectively. RESULTS: In the study, 2,955 patients were included and classified for analysis as 1,579 SH and 1,376 HH-DBT. Significant differences were observed in glycemic goal (35.53% SH versus 25.80% HH-DBT, p < 0.01), insulin use rate (26.66% SH versus 46.58% HH-DBT, p < 0.01), and severe hypoglycemia rate (1.32% SH versus 1.74% HH-DBT, p < 0.01). There were no differences in hypoglycemia rate (8.23% SH versus 10.53% HH-DBT) and hospital mortality. There was no increase in risk of mortality in the SH group adjusted for age, non-scheduled hospitalization, major surgical intervention, critical care, hypoglycemia, oncological disease, cardiovascular comorbidity, and prolonged hospitalization. CONCLUSIONS: In this study, we observed better glycemic control in patients with SH than in those with HH-DBT, and there was no difference in hospital mortality. SBDR - Society for Biomedical Diabetes Research 2021-10-31 /pmc/articles/PMC9380085/ /pubmed/34852895 http://dx.doi.org/10.1900/RDS.2021.17.50 Text en Copyright © by Lab & Life Press https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Original Data Russo, María Paula Fosser, Santiago Nicolas Marquez Elizondo, Cristina María Giunta, Diego Hernán Fuentes, Nora Angélica Grande-Ratti, María Florencia In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title | In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title_full | In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title_fullStr | In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title_full_unstemmed | In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title_short | In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia |
title_sort | in-hospital mortality and glycemic control in patients with hospital hyperglycemia |
topic | Original Data |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380085/ https://www.ncbi.nlm.nih.gov/pubmed/34852895 http://dx.doi.org/10.1900/RDS.2021.17.50 |
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