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Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1

OBJECTIVE: Vanishing white matter (VWM) is a leukodystrophy, characterized by stress‐sensitive neurological deterioration and premature death. It is currently without curative treatment. It is caused by bi‐allelic pathogenic variants in the genes encoding eukaryotic initiation factor 2B (eIF2B). eIF...

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Detalles Bibliográficos
Autores principales:	Witkamp, Diede, Oudejans, Ellen, Hu‐A‐Ng, Gino V., Hoogterp, Leoni, Krzywańska, Aleksandra M., Žnidaršič, Milo, Marinus, Kevin, de Veij Mestdagh, Christina F., Bartelink, Imke, Bugiani, Marianna, van der Knaap, Marjo S., Abbink, Truus E. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380178/ https://www.ncbi.nlm.nih.gov/pubmed/35778832 http://dx.doi.org/10.1002/acn3.51611

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