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Antibody therapy reverses biological signatures of COVID-19 progression

Understanding who is at risk of progression to severe coronavirus disease 2019 (COVID-19) is key to clinical decision making and effective treatment. We study correlates of disease severity in the COMET-ICE clinical trial that randomized 1:1 to placebo or to sotrovimab, a monoclonal antibody for the...

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Detalles Bibliográficos
Autores principales: Maher, M. Cyrus, Soriaga, Leah B., Gupta, Anil, Chen, Yi-Pei, di Iulio, Julia, Ledoux, Sarah, Smithey, Megan J., Cathcart, Andrea L., McKusick, Kathleen, Sun, David, Aldinger, Melissa, Alexander, Elizabeth, Purcell, Lisa, Ding, Xiao, Peppercorn, Amanda, Austin, Daren, Mogalian, Erik, Yeh, Wendy W., Shapiro, Adrienne E., Corti, Davide, Virgin, Herbert W., Pang, Phillip S., Telenti, Amalio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380250/
https://www.ncbi.nlm.nih.gov/pubmed/35977462
http://dx.doi.org/10.1016/j.xcrm.2022.100721