Modeling the early stages of Alzheimer’s disease by administering intracerebroventricular injections of human native Aβ oligomers to rats

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disease characterized by the accumulation of aggregated amyloid beta (Aβ) and hyperphosphorylated tau along with a slow decline in cognitive functions. Unlike advanced AD, the initial steps of AD pathophysiology have been p...

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Detalles Bibliográficos
Autores principales: Baerends, Eva, Soud, Katia, Folke, Jonas, Pedersen, Anna-Kathrine, Henmar, Simon, Konrad, Lisa, Lycas, Matthew D., Mori, Yuki, Pakkenberg, Bente, Woldbye, David P. D., Dmytriyeva, Oksana, Pankratova, Stanislava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380371/
https://www.ncbi.nlm.nih.gov/pubmed/35974377
http://dx.doi.org/10.1186/s40478-022-01417-5

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