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On model-based time trend adjustments in platform trials with non-concurrent controls
BACKGROUND: Platform trials can evaluate the efficacy of several experimental treatments compared to a control. The number of experimental treatments is not fixed, as arms may be added or removed as the trial progresses. Platform trials are more efficient than independent parallel group trials becau...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380382/ https://www.ncbi.nlm.nih.gov/pubmed/35971069 http://dx.doi.org/10.1186/s12874-022-01683-w |