On model-based time trend adjustments in platform trials with non-concurrent controls

BACKGROUND: Platform trials can evaluate the efficacy of several experimental treatments compared to a control. The number of experimental treatments is not fixed, as arms may be added or removed as the trial progresses. Platform trials are more efficient than independent parallel group trials becau...

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Detalles Bibliográficos
Autores principales: Roig, Marta Bofill, Krotka, Pavla, Burman, Carl-Fredrik, Glimm, Ekkehard, Gold, Stefan M., Hees, Katharina, Jacko, Peter, Koenig, Franz, Magirr, Dominic, Mesenbrink, Peter, Viele, Kert, Posch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380382/
https://www.ncbi.nlm.nih.gov/pubmed/35971069
http://dx.doi.org/10.1186/s12874-022-01683-w

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