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Aaptamine – a dual acetyl – and butyrylcholinesterase inhibitor as potential anti-Alzheimer’s disease agent

CONTEXT: Alzheimer’s disease (AD) is a neurodegenerative disorder that affects millions of people worldwide. Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) are promising therapeutic targets for AD. OBJECTIVE: To evaluate the inhibitory effects of aaptamine on two cholinesterases and i...

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Detalles Bibliográficos
Autores principales: Miao, Shuang, He, Qianqian, Li, Chen, Wu, Yan, Liu, Mengshan, Chen, Yongshou, Qi, Shizhou, Gong, Kaikai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380430/
https://www.ncbi.nlm.nih.gov/pubmed/35968601
http://dx.doi.org/10.1080/13880209.2022.2102657