Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the infectious agent that has caused the current coronavirus disease (COVID) pandemic. Viral infection relies on the viral S (spike) protein/cellular receptor ACE2 interaction. Disrupting this interaction would lead to early blockage of...

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Detalles Bibliográficos
Autores principales: Lapaillerie, Delphine, Charlier, Cathy, Guyonnet-Dupérat, Véronique, Murigneux, Emilie, Fernandes, Henrique S., Martins, Fábio G., Magalhães, Rita P., Vieira, Tatiana F., Richetta, Clémence, Subra, Frédéric, Lebourgeois, Samuel, Charpentier, Charlotte, Descamps, Diane, Visseaux, Benoît, Weigel, Pierre, Favereaux, Alexandre, Beauvineau, Claire, Buron, Frédéric, Teulade-Fichou, Marie-Paule, Routier, Sylvain, Gallois-Montbrun, Sarah, Meertens, Laurent, Delelis, Olivier, Sousa, Sérgio F., Parissi, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380551/
https://www.ncbi.nlm.nih.gov/pubmed/35861550
http://dx.doi.org/10.1128/aac.00083-22

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