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Synthesis and anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid against B16F10 cells via induction of endoplasmic reticulum stress-mediated autophagy through ERK/AKT signaling pathway

Melanoma is an aggressive form of cancer with poor prognosis and survival rates and limited therapeutic options. Here, we report the anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid (NPC-402), a derivative of glycyrrhtinic acid, from a reputed medicinal plant Glycyrrhiza glabra against B16F10...

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Detalles Bibliográficos
Autores principales:	Nazir, Lone A., Shahid, Naikoo H., Amit, Kumar, Umar, Sheikh A., Rajni, Sharma, Bharate, Sandip, Sangwan, Pyare L., Tasduq, Sheikh Abdullah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380594/ https://www.ncbi.nlm.nih.gov/pubmed/35982963 http://dx.doi.org/10.3389/fonc.2022.890299

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