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Application of immune enhanced organoids in modeling personalized Merkel cell carcinoma research

Merkel cell carcinoma (MCC) is a rare neuroendocrine cutaneous cancer, with incidence of less than 1/100,000, low survival rates and variable response to chemotherapy or immunotherapy. Herein we explore the application of patient tumor organoids (PTOs) in modeling personalized research in this rare...

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Detalles Bibliográficos
Autores principales: Forsythe, Steven D., Erali, Richard A., Laney, Preston, Sivakumar, Hemamylammal, Li, Wencheng, Skardal, Aleksander, Soker, Shay, Votanopoulos, Konstantinos I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380677/
https://www.ncbi.nlm.nih.gov/pubmed/35974123
http://dx.doi.org/10.1038/s41598-022-17921-6