Mpe1 senses the binding of pre-mRNA and controls 3′ end processing by CPF

Most eukaryotic messenger RNAs (mRNAs) are processed at their 3′ end by the cleavage and polyadenylation specificity factor (CPF/CPSF). CPF mediates the endonucleolytic cleavage of the pre-mRNA and addition of a polyadenosine (poly(A)) tail, which together define the 3′ end of the mature transcript....

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Detalles Bibliográficos
Autores principales: Rodríguez-Molina, Juan B., O’Reilly, Francis J., Fagarasan, Holly, Sheekey, Eleanor, Maslen, Sarah, Skehel, J. Mark, Rappsilber, Juri, Passmore, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380774/
https://www.ncbi.nlm.nih.gov/pubmed/35584695
http://dx.doi.org/10.1016/j.molcel.2022.04.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380774/
https://www.ncbi.nlm.nih.gov/pubmed/35584695
http://dx.doi.org/10.1016/j.molcel.2022.04.021

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